APRE — Aprea Therapeutics, Inc.

Nasdaq · Health Care · Pharmaceuticals · CIK 1781983 ·
Last close
$0.91
Market Cap
$11.27M
52W High
$1.12
52W Low
$0.60
ADV30
252,440
Next earnings
Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -3,430,412 -3,287,917 47,612,387 46,466,202 6,024,007
Dec 2025 0 -2,643,093 -2,455,630 15,933,401 14,599,347 3,491,719
Sep 2025 0 -3,117,388 -2,972,410 14,321,316 13,718,052 3,408,468
Jun 2025 0 -3,387,773 -3,238,870 17,309,710 16,532,199 3,895,029

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-12,894,439
Investing CF
$0
Financing CF
$4,640,238
CapEx
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.98
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-333,641,441
Inventory
Receivables
ST Investments
EBIT TTM
$-13,233,836
Pretax Income TTM
$-12,599,569
Interest Exp TTM
Analysts
3

Yahoo Snapshot (yfinance, live)

Total Revenue
$123,296
EBITDA
$-12,556,952
Free Cash Flow
$-5,607,762
Enterprise Value
$-33,975,204
Total Cash
$46,466,200
Total Debt
$0
Shares Out
12,382,776
Trailing EPS
$-1.49
Book Value
$3.47
ROE
-40.4%
ROA
-23.2%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -13,233,836 -12,599,569 15,933,401 3,491,719 -12,894,439
Dec 2024 0 -14,319,655 -12,958,711 23,979,493 4,672,038 -13,556,718
Dec 2023 0 -15,471,963 -14,286,756 22,650,174 5,696,668 -12,177,608
Dec 2022 0 -37,372,044 -112,662,027 30,155,827 4,512,149 -25,011,136

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-0.79

Peers — same industry

TickerNameMarket CapLastDaily %
KAPA Kairos Pharma, LTD. $11.07M $0.52
HOOK HOOKIPA Pharma Inc. $10.87M $1.09
BIVI BIOVIE INC. $10.86M $1.44
PRNAF ALTERITY THERAPEUTICS LTD $11.96M $0.00
KPRX KIORA PHARMACEUTICALS INC $11.97M $2.70

News headlines (Yahoo Finance, 1h cache)

Aprea Therapeutics Reports First Quarter 2026 Financial Results and Provides a Corporate Update
2026-05-13 10:30 · Yahoo
Oracle upgraded, Planet Fitness downgraded: Wall Street's top analyst calls
2026-05-07 13:45 · Yahoo
Aprea Therapeutics to Provide Clinical Update on ACESOT-1051 Phase 1 Trial Evaluating WEE1 Inhibitor, APR-1051, at ASCO 2026 Annual Meeting
2026-04-21 14:15 · Yahoo
Aprea Therapeutics Announces Closing of Oversubscribed $30 Million Private Placement
2026-04-01 12:30 · Yahoo
Aprea Therapeutics Announces Oversubscribed $30 Million Private Placement
2026-03-30 12:01 · Yahoo
Aprea Therapeutics Highlights Positive Emerging Clinical Activity for WEE1 Inhibitor, APR-1051, with a Confirmed Partial Response in the Ongoing Phase 1 ACESOT-1051 Trial
2026-03-30 12:00 · Yahoo
Aprea Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides a Corporate Update
2026-03-16 12:00 · Yahoo
Aprea Therapeutics Announces Additional Positive Clinical Activity for WEE1 Inhibitor, APR-1051, Including Second Partial Response in Ongoing ACESOT-1051 Trial
2026-02-18 13:00 · Yahoo
Aprea Therapeutics to Present at Oppenheimer 36th Annual Healthcare Life Sciences Conference
2026-02-17 13:00 · Yahoo
Aprea Therapeutics Strengthens Global Patent Portfolio in DNA Damage Response (DDR) Cancer Therapeutics, Paving Way for Pipeline Growth
2026-02-12 13:30 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.