BCYC — BICYCLE THERAPEUTICS PLC

Nasdaq · Health Care · Pharmaceuticals · CIK 1761612 ·
Last close
$4.33
Market Cap
$218.12M
52W High
$4.74
52W Low
$3.74
ADV30
305,584
Next earnings
2026-10-29
Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company's products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase II clinical trials for the treatment of high nectin-4 expressing tumors; nuzefatide pevedotin (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle tumor-targeted immune cell agonist molecule, which is in phase I/II targeting nectin-4 and agonizing CD137; and BT1702, a theranostic BRC molecule targeting MT1-MMP for which IND-enabling activities are ongoing. In addition, it develops Novel CNS targets, which is in preclinical trial targeting CNS disease; Novel neuromuscular targets, which is in preclinical trial targeting neuromuscular disease; and programs that are in preclinical trial targeting radiopharmaceutical. Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas. It has collaboration and license agreement with Bayer Consumer Care AG; Novartis Pharma AG; Ionis Pharmaceuticals, Inc.; Genentech, Inc; and AstraZeneca AB. Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Jun 2026 629,000 -54,628,000 -50,333,000 606,578,000 510,052,000 96,323,000
Mar 2026 887,000 -65,589,000 -60,825,000 652,396,000 559,474,000 98,076,000
Dec 2025 47,955,000 -24,657,000 -20,154,000 717,597,000 628,110,000 107,620,000
Sep 2025 11,734,000 -65,709,000 -59,100,000 763,954,000 648,325,000 145,475,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-206,050,000
Investing CF
$-2,226,000
Financing CF
$-149,000
CapEx
$-2,226,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-2.73
As of
2026-08-02

Balance + Analyst (yfinance extras)

Retained Earnings
$-1,010,909,000
Inventory
Receivables
$47,419,000
ST Investments
EBIT TTM
$-188,487,000
Pretax Income TTM
$-188,680,000
Interest Exp TTM
$193,000
Analysts
7

Yahoo Snapshot (yfinance, live)

Total Revenue
$61,205,000
EBITDA
$-200,812,000
Free Cash Flow
$-99,822,128
Enterprise Value
$-192,321,872
Total Cash
$510,052,000
Total Debt
$14,661,000
Shares Out
50,373,281
Trailing EPS
$-2.72
Book Value
$7.31
ROE
-32.3%
ROA
-17.9%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 72,586,000 -247,718,000 -218,960,000 717,597,000 107,620,000 -249,675,000
Dec 2024 35,275,000 -209,153,000 -169,031,000 956,868,000 163,808,000 -164,724,000
Dec 2023 26,976,000 -189,946,000 -180,664,000 595,344,000 224,412,000 -60,628,000
Dec 2022 14,463,000 -116,653,000 -112,717,000 410,609,000 139,826,000 -86,111,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-2.22

Max Pain — expiry 2026-09-18

max pain strike: $5.00 · spot: $4.39 · call oi: 1,566 · put oi: 3,793
Expected Move to 2026-09-18: ±$0.68 (15.38%) — implied range $3.71$5.06 · ATM straddle on $4.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
NBP NovaBridge Biosciences $218.58M $1.89
PEPG PepGen Inc. $220.94M $3.19
NGEN NERVGEN PHARMA CORP. $215.05M $2.00
ORGO Organogenesis Holdings Inc. $214.89M $1.67
KROS Keros Therapeutics, Inc. $213.74M $10.78

News headlines (Yahoo Finance, 1h cache)

European Equities Traded in the US as American Depositary Receipts Rise in Tuesday Trading
2026-06-02 15:08 · Yahoo
Morgan Stanley Updates Bicycle Therapeutics plc (BCYC) Outlook Amid Pipeline Refocus
2026-04-17 13:58 · Yahoo
Wall Street Analysts Believe Bicycle Therapeutics (BCYC) Could Rally 137.88%: Here's is How to Trade
2026-04-16 13:55 · Yahoo
Bicycle Therapeutics Reports Recent Business Progress and Second Quarter 2026 Financial Results
2026-07-30 11:00 · Yahoo
European Equities Traded in the US as American Depositary Receipts Declining in Thursday Trading
2026-04-16 15:05 · Yahoo
RBC Capital Lowers its Price Target on Bicycle Therapeutics plc (BCYC) to $7 from $11
2026-04-04 12:16 · Yahoo
After Plunging 20.2% in 4 Weeks, Here's Why the Trend Might Reverse for Bicycle Therapeutics (BCYC)
2026-03-24 13:35 · Yahoo
Bicycle Therapeutics (BCYC) Loses 19.0% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner
2026-03-23 13:35 · Yahoo
Bicycle Therapeutics (BCYC) Appoints Travis Thompson as CFO Following Leadership Transitions
2026-03-14 10:21 · Yahoo
European Equities Traded in the US as American Depositary Receipts Start Week Lower
2026-02-23 16:02 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.