CNTA — Centessa Pharmaceuticals plc

Nasdaq · Health Care · Pharmaceuticals · CIK 1847903 ·
Last close
$39.78
Market Cap
$6.16B
52W High
$40.26
52W Low
$25.06
ADV30
1,774,892
Next earnings
2026-05-14
Centessa Pharmaceuticals plc, together with its subsidiaries, discovers, develops, and delivers orexin-based neuroscience therapeutics in the United Kingdom and the United States. The company develops ORX750, an orexin receptor 2 agonist, which is in Phase IIa clinical trial for the treatment of central disorders of hypersomnolence, including narcolepsy type 1 and 2, as well as idiopathic hypersomnia. It also engages in the development of ORX142 which is in Phase I clinical trial for the treatment of neurological and neurodegenerative disorders; ORX489 which is in Phase I clinical trial for the treatment of neuropsychiatric disorders; and LockBody, an early-stage immuno-oncology program technology platform. The company was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -79,773,000 -79,241,000 641,763,000 62,431,000 154,415,000
Dec 2025 0 -68,472,000 -66,163,000 687,495,000 61,299,000 160,632,000
Sep 2025 0 -53,790,000 -54,891,000 448,300,000 50,811,000 146,726,000
Jun 2025 0 -54,653,000 -50,343,000 492,127,000 44,242,000 147,208,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-193,817,000
Investing CF
$-418,531,000
Financing CF
$291,528,000
CapEx
$-245,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.83
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-1,186,234,000
Inventory
Receivables
$60,341,000
ST Investments
$233,281,000
EBIT TTM
$-184,254,000
Pretax Income TTM
$-195,713,000
Interest Exp TTM
$11,459,000
Analysts
7

Yahoo Snapshot (yfinance, live)

Total Revenue
$0
EBITDA
$-256,344,992
Free Cash Flow
$-128,715,624
Enterprise Value
$5,992,442,368
Total Cash
$276,588,992
Total Debt
$118,555,000
Shares Out
154,728,966
Trailing EPS
$-1.78
Book Value
$3.15
ROE
-57.4%
ROA
-27.4%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 15,000,000 -207,692,000 -197,532,000 687,495,000 160,632,000 -193,817,000
Dec 2024 0 -201,055,000 -235,757,000 576,798,000 175,253,000 -142,055,000
Dec 2023 6,853,000 -171,283,000 -151,085,000 360,246,000 124,002,000 -160,342,000
Dec 2022 0 -210,283,000 -216,207,000 444,307,000 108,138,000 -200,546,000

TTM Snapshot

Revenues TTM
$1,031,000
NetIncome TTM
$-135,918,000
OpCashFlow TTM
$0
Assets (Latest)
$576,798,000
Forward EPS
$-1.90

Peers — same industry

TickerNameMarket CapLastDaily %
RYTM RHYTHM PHARMACEUTICALS, INC. $6.16B $89.82
TERN Terns Pharmaceuticals, Inc. $6.12B $52.95
ALKS Alkermes plc. $6.23B $37.35
TGTX TG THERAPEUTICS, INC. $6.08B $39.73
MIRM Mirum Pharmaceuticals, Inc. $6.03B $98.90

News headlines (Yahoo Finance, 1h cache)

Lilly Goes on $20 Billion Buying Spree as Company Seeks Next Act
2026-05-26 16:54 · Yahoo
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Eli Lilly Sells $9 Billion of Bonds to Fund Acquisitions
2026-05-06 20:25 · Yahoo
Update: Market Chatter: Eli Lilly Plans to Sell About $8 Billion of Bonds to Fund Acquisitions
2026-05-06 15:35 · Yahoo
Is It Too Late To Consider Centessa Pharmaceuticals (CNTA) After A 191% One Year Surge?
2026-05-03 19:12 · Yahoo
Guggenheim Raises PT on Eli Lilly (LLY) Amid Several Acquisition Deals
2026-04-29 16:03 · Yahoo
Is This $6.3 Billion Deal a Game Changer for Eli Lilly?
2026-04-16 13:50 · Yahoo
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2026-04-13 10:50 · Yahoo
Looks Like M&A Week in 3 Different Sectors
2026-04-08 16:22 · Yahoo
Pharma, Biotech Giants Ramp Up M&A in Q1 to Boost Pipelines
2026-04-06 19:06 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.