CYCN — Cyclerion Therapeutics, Inc.

Nasdaq · Health Care · Pharmaceuticals · CIK 1755237 ·
Last close
$3.20
Market Cap
$13.86M
52W High
$8.48
52W Low
$1.27
ADV30
110,650
Next earnings
Cyclerion Therapeutics, Inc., a biopharmaceutical company, engages in the development of treatments for serious diseases serious diseases with novel sGC stimulators in both the central nervous system (CNS) and the periphery. The company is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to treat cardiovascular diseases; and Praliciguat, a systemic sGC stimulator for the treatment of rare kidney disease. It has a license agreement with Akebia to develop, manufacture, medical affair, and commercializes Praliciguat and other related products. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -3,209,000 -3,177,000 8,505,000 2,823,000 1,714,000
Dec 2025 1,025,000 -838,000 -799,000 9,985,000 3,240,000 900,000
Sep 2025 875,000 -1,006,000 -976,000 10,415,000 4,568,000 877,000
Jun 2025 93,000 -1,672,000 -324,000 9,370,000 3,006,000 800,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-3,314,000
Investing CF
$0
Financing CF
$3,322,000
CapEx
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.26
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-271,020,000
Inventory
Receivables
$1,000,000
ST Investments
EBIT TTM
$-4,973,000
Pretax Income TTM
$-3,528,000
Interest Exp TTM
Analysts
1

Yahoo Snapshot (yfinance, live)

Total Revenue
$1,993,000
EBITDA
Free Cash Flow
$-2,589,125
Enterprise Value
$10,947,399
Total Cash
$2,823,000
Total Debt
$0
Shares Out
4,330,314
Trailing EPS
$-1.31
Book Value
$1.60
ROE
-67.8%
ROA
-45.8%
Div Yield

Annual Trend (SEC EDGAR, last 5y)

Revenues vs Net Income (last 5y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 2,074,000 -4,973,000 -3,528,000 9,985,000 900,000 -3,314,000
Dec 2024 2,000,000 -3,628,000 -3,057,000 9,575,000 725,000 -4,333,000
Dec 2023 0 -9,647,000 -5,263,000 13,374,000 2,086,000 -21,245,000
Dec 2022 297,000 -18,540,000 -44,078,000 18,079,000 7,627,000 -40,611,000
Dec 2021

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-1.31

Peers — same industry

TickerNameMarket CapLastDaily %
BLRX BioLineRx Ltd. $13.75M $3.16
TOVX Theriva Biologics, Inc. $13.63M $0.30
GDTC CytoMed Therapeutics Ltd $13.61M $1.15
GTBP GT Biopharma, Inc. $14.14M $0.39
HOTH Hoth Therapeutics, Inc. $13.55M $0.71

News headlines (Yahoo Finance, 1h cache)

Cyclerion Therapeutics (CYCN) Merges With Korsana Biosciences to Advance Alzheimer’s Pipeline
2026-04-20 14:15 · Yahoo
Penny Stock CYCN Surged More Than 300% Yesterday. Why, And Should You Chase the Rally Here?
2026-04-02 13:15 · Yahoo
Top Midday Gainers
2026-04-01 17:51 · Yahoo
Cyclerion Therapeutics and Korsana Biosciences Announce Merger Agreement
2026-04-01 11:05 · Yahoo
CYCN: Positive Feedback from FDA Sets Stage for Phase 2 Trial of CYC-126 in 2H26
2026-02-23 11:53 · Yahoo
Cyclerion Therapeutics Announces Progress Toward CYC-126 Phase 2 Proof-of-Concept Study with FDA Feedback and Formation of Clinical Advisory Board
2026-02-17 12:00 · Yahoo
CYCN: Engineering a Reset; Initiating Coverage of Cyclerion Therapeutics…
2026-02-02 12:14 · Yahoo
BC-Most Active Stocks
2026-01-06 15:30 · Yahoo
Cyclerion Therapeutics Announces Strategic Agreement with Medsteer and Progress Toward Initiating Phase 2 Proof-of-Concept Study for CYC-126 in Treatment-Resistant Depression
2026-01-05 21:01 · Yahoo
Akebia Therapeutics Sets Rare Kidney Drug Plan After Q32 Bio Deal
2025-12-01 13:40 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.