LIXT — LIXTE BIOTECHNOLOGY HOLDINGS, INC.

Nasdaq · Health Care · Pharmaceuticals · CIK 1335105 ·
Last close
$5.65
Market Cap
$69.96M
52W High
$6.11
52W Low
$2.36
ADV30
71,249
Next earnings
Lixte Biotechnology Holdings, Inc., a clinical-stage biopharmaceutical and proton cancer therapy company, focuses on identifying targets for cancer drug development, and developing and commercializing cancer therapies. Its lead product candidate, LB-100 is in phase 1b clinical trials combined with Atezolizumab for patients with microsatellite stable metastatic colorectal cancer. The company's LB-100 combined with doxorubicin in advanced soft tissue sarcoma is under Phase 1b portion; and LB-100 combined with dostarlimab that is in phase 1b/2 for ovarian clear cell carcinoma. The company has a clinical trial research agreement with the Netherlands Cancer Institute; collaboration agreement for an investigator-initiated clinical trial with the Spanish Sarcoma Group; and a development collaboration agreement with the Netherlands Cancer Institute. Lixte Biotechnology Holdings, Inc. was founded in 2005 and is based in Boca Raton, Florida.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -1,987,407 -1,923,676 10,865,298 3,250,650 1,686,706
Dec 2025 0 -1,824,518 -2,543,894 12,733,621 5,106,872 1,772,070
Sep 2025 0 -1,801,354 -1,980,398 5,433,676 2,887,874 521,422
Jun 2025 0 -774,809 -775,673 1,188,578 887,212 537,122

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-3,070,618
Investing CF
$-535,102
Financing CF
$10,311,000
CapEx
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.35
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-58,077,213
Inventory
Receivables
ST Investments
$2,454,473
EBIT TTM
$-6,000,362
Pretax Income TTM
$-6,009,520
Interest Exp TTM
$9,158
Analysts

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -5,107,621 -6,009,520 12,733,621 1,772,070 -3,070,618
Dec 2024 0 -3,572,789 -3,585,965 1,145,503 318,284 -3,164,536
Dec 2023 0 -5,090,236 -5,087,029 4,308,620 313,858 -4,293,265
Dec 2022 0 -6,311,481 -6,312,535 5,560,983 395,756 -4,611,737

Peers — same industry

TickerNameMarket CapLastDaily %
ACRV Acrivon Therapeutics, Inc. $71.48M $1.67
FLNA FILANA THERAPEUTICS, INC. $68.11M $1.41
RFL Rafael Holdings, Inc. $67.62M $1.32
MNOV MEDICINOVA INC $67.43M $1.37
XBIT XBiotech Inc. $73.17M $2.40

News headlines (Yahoo Finance, 1h cache)

LIXTE Biotechnology Files First Quarter 2026 Quarterly Report on Form 10-Q; Provides Operational Progress Update
2026-05-14 21:18 · Yahoo
LIXTE Biotechnology Holdings (LIXT) Unlocking New Potential in Precision Cancer Treatment
2026-04-27 18:14 · Yahoo
LIXTE Biotechnology Holdings (LIXT) Positions LB-100 as Novel Approach in Cancer Treatment Landscape
2026-04-20 19:00 · Yahoo
Precision Oncology Is Shifting Toward Combination Strategies, Ultimately Changing How New Therapies Are Built
2026-04-17 19:30 · Yahoo
LIXTE Biotechnology (LIXT) Reports Interim Ovarian Cancer Trial Results at SGO Conference
2026-04-13 19:30 · Yahoo
Favorable Results of Ovarian Cancer Study Presented at Annual Society of Gynecological Care Conference
2026-04-13 12:00 · Yahoo
Lixte Biotech Holdings (LIXT) Advances Precision Oncology Strategy With LB-100, Expands Clinical and Strategic Partnerships
2026-04-10 19:00 · Yahoo
LIXTE Biotechnology Holdings (LIXT) Files 2025 Form 10-K, Highlights Transformational Year
2026-04-02 18:30 · Yahoo
LIXTE Biotechnology (LIXT) Has the World's Only Clinical-Stage PP2A Inhibitor, Poised to Improve Cancer Treatment Outcomes
2026-04-01 18:30 · Yahoo
LIXTE Biotechnology Files 2025 Annual Report on Form 10K, Provides Operational Highlights of Transformative Year
2026-03-31 19:45 · Yahoo

Recent Insider Activity

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