NCNA — NuCana plc

Nasdaq · Health Care · Pharmaceuticals · CIK 1709626 ·
Last close
$2.00
Market Cap
$8.32M
52W High
$2.33
52W Low
$1.33
ADV30
32,683
Next earnings
NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer in the United States. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company is developing medicines to overcome the limitations of nucleoside analogs and generate concentrations of anti-cancer metabolites in cancer cells. Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer; Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer; and Phase 1b/2 modular clinical trial for patients with advanced solid tumors and lung cancer. It also developing NUC-7738, a ProTide transformation of 3'-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors. It has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is based in Edinburgh, the United Kingdom.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -4,781,000 -3,865,000 27,553,000 21,529,000 5,186,000
Dec 2025 0 -2,843,000 -2,485,000 29,834,000 24,251,000 5,507,000
Sep 2025 0 -3,571,000 -281,000 32,315,000 25,249,000 6,389,000
Jun 2025 0 -11,627,000 -24,114,000 16,218,000 8,443,000 8,834,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-7,467,000
Investing CF
$159,000
Financing CF
$25,006,000
CapEx
$-193,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-100.00
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-252,334,000
Inventory
Receivables
$1,864,000
ST Investments
EBIT TTM
$-20,833,000
Pretax Income TTM
$-30,521,000
Interest Exp TTM
Analysts

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -20,833,000 -29,353,000 29,834,000 5,507,000 -7,467,000
Dec 2024 0 -23,005,000 -18,997,000 14,774,000 8,820,000 -19,118,000
Dec 2023 0 -31,125,000 -27,632,000 27,811,000 12,924,000 -26,439,000
Dec 2022 0 -43,717,000 -32,021,000 58,254,000 19,752,000 -23,158,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-9.43

Peers — same industry

TickerNameMarket CapLastDaily %
ACXP Acurx Pharmaceuticals, Inc. $8.34M $1.94
MCUJF MEDICURE INC $8.35M $0.80
IMRN Immuron Ltd $8.25M $1.01
ENVB Enveric Biosciences, Inc. $8.21M $2.23
GNPX Genprex, Inc. $8.17M $0.77

News headlines (Yahoo Finance, 1h cache)

European Equities Traded in the US as American Depositary Receipts Track Higher in Tuesday Trading
2026-05-26 15:09 · Yahoo
European Equities Traded in the US as American Depositary Receipts Little Changed in Thursday Trading
2026-05-21 15:05 · Yahoo
European Equities Traded in the US as American Depositary Receipts Trend Lower in Tuesday Trading
2026-05-19 15:27 · Yahoo
European Equities Traded in the US as American Depositary Receipts Open Week Tracking Higher in Monday Trading
2026-05-18 15:11 · Yahoo
European Equities Traded in the US as American Depositary Receipts Down Sharply in Friday Trading
2026-05-15 15:04 · Yahoo
NuCana Reports First Quarter 2026 Financial Results and Provides Business Update
2026-05-14 20:01 · Yahoo
European Equities Traded in the US as American Depositary Receipts Tracking Higher in Thursday Trading
2026-05-14 15:05 · Yahoo
European Equities Traded in the US as American Depositary Receipts Climb Sharply Higher in Wednesday Trading
2026-05-06 15:10 · Yahoo
European Equities Traded in the US as American Depositary Receipts Start Week Lower
2026-05-04 15:09 · Yahoo
European Equities Traded in the US as American Depositary Receipts Track Lower in Monday Trading
2026-04-27 15:17 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.