PLRX — PLIANT THERAPEUTICS, INC.

Nasdaq · Health Care · Pharmaceuticals · CIK 1746473 ·
Last close
$1.24
Market Cap
$76.78M
52W High
$1.43
52W Low
$1.13
ADV30
516,167
Next earnings
Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company's lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of avß8 and avß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -21,772,000 -20,040,000 202,596,000 22,190,000 37,430,000
Dec 2025 0 -23,577,000 -23,577,000 225,228,000 45,445,000 44,023,000
Sep 2025 0 -28,269,000 -26,301,000 276,600,000 93,732,000 76,294,000
Jun 2025 0 -45,592,000 -43,300,000 299,824,000 86,820,000 79,742,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-128,336,000
Investing CF
$134,290,000
Financing CF
$-31,697,000
CapEx
$-1,479,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-2.44
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-859,396,000
Inventory
Receivables
$823,000
ST Investments
$145,499,000
EBIT TTM
$-146,785,000
Pretax Income TTM
$-149,344,000
Interest Exp TTM
$2,559,000
Analysts
3

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -156,373,000 -149,344,000 225,228,000 44,023,000 -128,336,000
Dec 2024 0 -228,365,000 -210,304,000 396,949,000 92,868,000 -155,503,000
Dec 2023 1,580,000 -184,145,000 -161,336,000 512,154,000 38,578,000 -116,361,000
Dec 2022 9,685,000 -127,200,000 -123,321,000 350,613,000 37,271,000 -94,631,000

TTM Snapshot

Revenues TTM
$-120,936,000
NetIncome TTM
$-156,910,000
OpCashFlow TTM
$0
Assets (Latest)
$396,949,000
Forward EPS
$-1.03

Max Pain — expiry 2026-07-17

max pain strike: $1.00 · spot: $1.24 · call oi: 169 · put oi: 1,370
Expected Move to 2026-07-17: ±$0.42 (33.87%) — implied range $0.82$1.66 · ATM straddle on $1.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
HYFT MindWalk Holdings Corp. $76.14M $1.63
GANX Gain Therapeutics, Inc. $77.63M $1.82
ACET Adicet Bio, Inc. $77.87M $8.33
RLYB Rallybio Corp $77.88M $14.70
OSTX OS Therapies Inc $77.94M $1.75

News headlines (Yahoo Finance, 1h cache)

Pliant Therapeutics Provides Corporate Update and Reports First Quarter 2026 Financial Results
2026-05-11 20:05 · Yahoo
Pliant Therapeutics to Participate in the RBC Capital Markets Global Healthcare Conference
2026-05-06 12:30 · Yahoo
Pliant Therapeutics Announces First Patient Dosed in FORTIFY, the Phase 1b Indication Expansion Trial Evaluating PLN-101095 in Patients with ICI-Refractory Solid Tumors
2026-04-30 12:30 · Yahoo
Pliant Therapeutics Announces Presentation of Updated Data from the Phase 1 Trial of PLN-101095 in Patients with ICI-Refractory Solid Tumors at the 2026 AACR Annual Meeting
2026-04-18 17:31 · Yahoo
Pliant Therapeutics Announces Upcoming Presentation of Phase 1 Clinical Trial of PLN-101095 in Patients with Solid Tumors at the 2026 AACR Annual Meeting
2026-03-18 13:00 · Yahoo
Pliant Therapeutics Provides Corporate Update and Reports Fourth Quarter 2025 Financial Results
2026-03-11 20:05 · Yahoo
Pliant Therapeutics Pivots to Oncology, Highlights Early PLN-101095 Responses at Oppenheimer Conference
2026-03-01 15:39 · Yahoo
Pliant Therapeutics to Participate in the Oppenheimer Healthcare Life Science Conference
2026-02-23 13:00 · Yahoo
Enhanced Genomics Appoints Dr Katerina Leftheris to Its Board of Directors
2026-01-09 14:10 · Yahoo
Pliant Therapeutics Announces Interim Data from PLN-101095 in Patients with Immune Checkpoint Inhibitor-Refractory Advanced Solid Tumors
2025-12-04 12:30 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.