PRLD — Prelude Therapeutics Inc

Nasdaq · Health Care · Pharmaceuticals · CIK 1678660 ·
Last close
$4.09
Market Cap
$265.51M
52W High
$5.54
52W Low
$2.54
ADV30
517,698
Next earnings
Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 4,580,000 -14,177,000 -10,385,000 119,642,000 21,756,000 59,459,000
Dec 2025 5,640,000 -17,348,000 -16,457,000 141,315,000 35,256,000 72,678,000
Sep 2025 6,500,000 -20,418,000 -19,725,000 94,755,000 47,532,000 36,221,000
Jun 2025 0 -32,194,000 -31,231,000 114,918,000 25,752,000 39,080,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-56,302,000
Investing CF
$53,459,000
Financing CF
$24,816,000
CapEx
$-183,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.52
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-683,061,000
Inventory
Receivables
ST Investments
$67,958,000
EBIT TTM
$-104,566,000
Pretax Income TTM
$-99,498,000
Interest Exp TTM
Analysts
4

Yahoo Snapshot (yfinance, live)

Total Revenue
$16,720,000
EBITDA
$-81,170,000
Free Cash Flow
$-17,930,124
Enterprise Value
$276,252,448
Total Cash
$81,554,000
Total Debt
$17,721,000
Shares Out
64,917,172
Trailing EPS
$-1.00
Book Value
$0.95
ROE
-95.2%
ROA
-39.7%
Div Yield

Annual Trend (SEC EDGAR, last 5y)

Revenues vs Net Income (last 5y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 12,140,000 -104,566,000 -99,498,000 141,315,000 72,678,000 -56,302,000
Dec 2024 7,000,000 -139,714,000 -127,173,000 175,515,000 44,056,000 -102,888,000
Dec 2023 0 -132,277,000 -121,832,000 277,665,000 40,575,000 -107,063,000
Dec 2022 0 -123,540,000 -115,438,000 220,500,000 25,063,000 -83,729,000
Dec 2021

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-0.83

Max Pain — expiry 2026-06-18

max pain strike: $5.00 · spot: $4.09 · call oi: 1,841 · put oi: 505
Expected Move to 2026-06-18: ±$1.65 (40.34%) — implied range $2.44$5.74 · ATM straddle on $5.00 strike

Peers — same industry

TickerNameMarket CapLastDaily %
RLFTY MindMaze Therapeutics Holding SA $264.43M $1.73
NVCT Nuvectis Pharma, Inc. $267.91M $10.10
TRDA Entrada Therapeutics, Inc. $260.10M $6.70
ALXO ALX ONCOLOGY HOLDINGS INC $259.71M $1.93
FHTX Foghorn Therapeutics Inc. $256.58M $4.37

News headlines (Yahoo Finance, 1h cache)

Earnings Beat: Prelude Therapeutics Incorporated (NASDAQ:PRLD) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their Forecasts
2026-05-16 14:22 · Yahoo
Prelude Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update
2026-05-12 11:01 · Yahoo
Wall Street Analysts Think Prelude Therapeutics (PRLD) Could Surge 33.59%: Read This Before Placing a Bet
2026-05-08 13:55 · Yahoo
Prelude Therapeutics (PRLD) Presents Preclinical Data for KAT6A Degarader PRT13722 in Breast Cancer
2026-05-01 09:24 · Yahoo
Prelude Therapeutics Presents Preclinical Data from Development Candidate, PRT13722, a First-in-Class, Orally Bioavailable, Potent and Highly Selective KAT6A Degrader at American Association for Cance
2026-04-20 10:00 · Yahoo
Prelude Therapeutics Announces the Appointment of Charles Morris, M.D. as Chief Medical Officer
2026-04-15 11:30 · Yahoo
Myriad Genetics And 2 Other Penny Stocks To Watch Closely
2026-04-06 18:05 · Yahoo
Prelude Therapeutics Announces Acceptance of Preclinical Abstract for PRT13722, a First-in-Class Oral KAT6A Selective Degrader at the 2026 AACR Annual Meeting
2026-03-17 20:31 · Yahoo
Prelude Therapeutics Reports Full Year 2025 Financial Results and Provides Program Outlook for 2026
2026-03-10 11:01 · Yahoo
Sana Biotechnology (SANA) Appoints Industry Veteran Brian Piper as New CFO
2026-02-26 19:27 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.