PRTA — PROTHENA CORP PUBLIC LTD CO

Nasdaq · Health Care · Pharmaceuticals · CIK 1559053 ·
Last close
$10.06
Market Cap
$526.67M
52W High
$11.80
52W Low
$8.38
ADV30
491,964
Next earnings
Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau antibody which is in Phase 2 clinical trial to treat Alzheimer's disease; PRX019, an investigational antibody which is in Phase 1 clinical trial for the treatment of neurodegenerative diseases; and PRX123, a Dual Aß-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease. In addition, it develops discovery- and late-preclinical-stage programs include TDP-43 CYTOPE for the treatment of amyotrophic lateral sclerosis; PRX012, a next-generation anti-Aß antibody which is in phase 1 clinical trial to treat Alzheimer's disease; and PRX012-TfR, a preclinical program for the treatment of Alzheimer's disease. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 51,084,000 25,791,000 32,721,000 349,894,000 329,462,000 37,278,000
Dec 2025 21,000 -27,211,000 -21,589,000 326,804,000 307,531,000 46,330,000
Sep 2025 2,415,000 -39,761,000 -36,541,000 352,628,000 330,843,000 57,639,000
Jun 2025 4,420,000 -52,007,000 -125,767,000 399,066,000 371,435,000 74,735,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-163,580,000
Investing CF
$-138,000
Financing CF
$-139,000
CapEx
$-181,000
Dividends Paid
Buybacks
$-139,000
EPS Diluted TTM
$-4.54
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-1,346,433,000
Inventory
Receivables
$0
ST Investments
EBIT TTM
$-184,560,000
Pretax Income TTM
$-200,829,000
Interest Exp TTM
Analysts
5

Yahoo Snapshot (yfinance, live)

Total Revenue
$57,940,000
EBITDA
$-92,332,000
Free Cash Flow
$-31,584,500
Enterprise Value
$192,824,320
Total Cash
$329,462,016
Total Debt
$7,654,000
Shares Out
52,353,237
Trailing EPS
$-2.81
Book Value
$5.21
ROE
-40.3%
ROA
-13.8%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 9,684,000 -184,560,000 -244,092,000 326,804,000 46,330,000 -163,580,000
Dec 2024 135,157,000 -154,561,000 -122,310,000 547,108,000 60,182,000 -150,050,000
Dec 2023 91,370,000 -191,036,000 -147,028,000 696,382,000 135,017,000 -133,906,000
Dec 2022 53,905,000 -131,557,000 -116,949,000 758,035,000 135,993,000 -108,821,000

TTM Snapshot

Revenues TTM
$226,527,000
NetIncome TTM
$26,389,000
OpCashFlow TTM
$0
Assets (Latest)
$547,108,000
Forward EPS
$-1.31

Peers — same industry

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NIKA NIKA PHARMACEUTICALS, INC $534.76M $0.51
RIGL RIGEL PHARMACEUTICALS INC $539.71M $29.17
AQST Aquestive Therapeutics, Inc. $511.84M $4.08
CBIO CRESCENT BIOPHARMA, INC. $561.09M $20.35

News headlines (Yahoo Finance, 1h cache)

Earnings Beat: Prothena Corporation plc Just Beat Analyst Forecasts, And Analysts Have Been Updating Their Models
2026-05-11 13:17 · Yahoo
Prothena Reports First Quarter 2026 Financial Results and Business Highlights
2026-05-07 20:05 · Yahoo
Prothena to Report First Quarter 2026 Financial Results on May 7
2026-04-30 20:05 · Yahoo
Stock Market Today, April 29: KalVista Pharmaceuticals Surges on Chiesi Group Acquisition Announcement
2026-04-29 22:07 · Yahoo
3 Growth Companies Insiders Are Eager To Hold
2026-04-29 11:36 · Yahoo
Prothena Announces Novo Nordisk Obtains Fast Track Designation from the U.S. FDA for Coramitug (PRX004) in ATTR Amyloidosis with Cardiomyopathy
2026-04-27 20:05 · Yahoo
Prothena Announces Leadership Team Updates
2026-04-10 20:05 · Yahoo
AZN Posts Data From Hypophosphatasia Program on Efzimfotase Alfa
2026-04-01 15:04 · Yahoo
Top Growth Companies With High Insider Ownership In March 2026
2026-03-31 17:36 · Yahoo
Sanofi Gets EU Nod for Rezurock in Chronic Graft-Vs-Host Disease
2026-03-31 16:12 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.