PTGX — Protagonist Therapeutics, Inc

Nasdaq · Health Care · Pharmaceuticals · CIK 1377121 ·
Last close
$154.72
Market Cap
$10.01B
52W High
$160.81
52W Low
$92.75
ADV30
527,648
Next earnings
2026-11-05
Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Jun 2026 213,475,000 158,766,000 162,849,000 885,544,000 420,078,000 44,001,000
Mar 2026 56,368,000 -3,648,000 3,783,000 697,459,000 193,712,000 41,986,000
Dec 2025 7,437,000 -50,355,000 -44,384,000 668,188,000 128,390,000 53,481,000
Sep 2025 4,712,000 -46,421,000 -39,339,000 701,688,000 113,713,000 56,251,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$131,197,000
Investing CF
$78,722,000
Financing CF
$41,613,000
CapEx
$-615,000
Dividends Paid
Buybacks
EPS Diluted TTM
$1.03
As of
2026-08-09

Balance + Analyst (yfinance extras)

Retained Earnings
$-304,039,000
Inventory
Receivables
$19,642,000
ST Investments
$362,498,000
EBIT TTM
$58,342,000
Pretax Income TTM
$84,338,000
Interest Exp TTM
Analysts
13

Yahoo Snapshot (yfinance, live)

Total Revenue
$281,992,000
EBITDA
$59,883,000
Free Cash Flow
$96,145,752
Enterprise Value
$9,238,305,792
Total Cash
$782,576,000
Total Debt
$9,216,000
Shares Out
64,708,285
Trailing EPS
$1.04
Book Value
$13.01
ROE
11.0%
ROA
4.5%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 46,016,000 -158,127,000 -130,149,000 668,188,000 53,481,000 57,671,000
Dec 2024 434,433,000 252,843,000 275,188,000 744,725,000 69,430,000 184,152,000
Dec 2023 60,000,000 -93,652,000 -78,955,000 357,951,000 21,274,000 -70,236,000
Dec 2022 26,581,000 -131,373,000 -127,393,000 247,928,000 32,320,000 -108,137,000

TTM Snapshot

Revenues TTM
$0
NetIncome TTM
$-7,084,000
OpCashFlow TTM
$0
Assets (Latest)
$93,990,000
Forward EPS
$0.06

Peers — same industry

TickerNameMarket CapLastDaily %
ABVX Abivax S.A. $10.13B $116.15
SMMT Summit Therapeutics Inc. $10.16B $12.73
RDY DR REDDYS LABORATORIES LTD $10.18B $12.22
PRAX Praxis Precision Medicines, Inc. $10.28B $368.03
IONS IONIS PHARMACEUTICALS INC $10.31B $62.04

News headlines (Yahoo Finance, 1h cache)

Protagonist Therapeutics Reports Granting of Inducement Awards
2026-08-18 20:05 · Yahoo
Protagonist Therapeutics (PTGX) Beats Q2 Earnings Estimates
2026-08-05 21:25 · Yahoo
Protagonist Reports Second Quarter 2026 Financial Results and Provides Corporate Update
2026-08-05 20:05 · Yahoo
Protagonist Therapeutics (PTGX) After Icotyde Launch And Rusfertide Review Looks Undervalued
2026-07-09 14:14 · Yahoo
Silence Therapeutics' Divesiran Data Support Best-in-Class Potential, Morgan Stanley Says
2026-08-11 15:05 · Yahoo
J&J's Strong Pipeline Momentum Offers Multiple Growth Catalysts Ahead
2026-08-24 14:38 · Yahoo
4 Psoriasis Drug Stocks to Watch During Psoriasis Awareness Month 2026
2026-08-11 13:44 · Yahoo
J&J Trading Above 200- & 50-Day SMAs: Buy, Sell or Hold the Stock?
2026-08-11 13:12 · Yahoo
Surging Earnings Estimates Signal Upside for Protagonist Therapeutics (PTGX) Stock
2026-08-07 16:20 · Yahoo
Alnylam Pharmaceuticals (ALNY) Misses Q2 Earnings and Revenue Estimates
2026-07-30 13:35 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.