SLN — Silence Therapeutics plc

Nasdaq · Health Care · Pharmaceuticals · CIK 1479615 · United Kingdom
Last close
$6.64
Market Cap
$313.64M
52W High
$8.40
52W Low
$4.75
ADV30
306,150
Next earnings
Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 422,000 411,000 -15,737,000 -14,957,000 115,123,000 5,657,000 65,721,000
Dec 2025 34,000 22,000 -12,461,000 -11,770,000 131,442,000 11,277,000 69,138,000
Sep 2025 159,000 95,000 -26,244,000 -20,958,000 146,790,000 82,031,000 72,727,000
Jun 2025 224,000 139,000 -22,639,000 -27,354,000 165,233,000 41,739,000 71,078,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-62,271,000
Investing CF
$-47,992,000
Financing CF
$15,000
CapEx
$-110,768
Dividends Paid
Buybacks
EPS Diluted TTM
$-2.37
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-562,572,000
Inventory
Receivables
$24,614,000
ST Investments
$73,837,000
EBIT TTM
$-89,753,000
Pretax Income TTM
$-88,601,000
Interest Exp TTM
$11,511,234
Analysts
4

Yahoo Snapshot (yfinance, live)

Total Revenue
$839,000
EBITDA
$-71,083,000
Free Cash Flow
$-44,562,752
Enterprise Value
$808,621,824
Total Cash
$70,078,000
Total Debt
$136,000
Shares Out
47,234,613
Trailing EPS
$-1.62
Book Value
$1.32
ROE
-92.6%
ROA
-29.8%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 559,000 -89,753,000 -88,612,000 131,442,000 69,138,000 -62,271,000
Dec 2024 43,258,000 -63,319,000 -45,309,000 202,635,000 68,612,000 -67,640,000
Dec 2023 31,643,000 -64,383,000 -54,228,000 119,448,000 97,455,000 -49,462,000
Dec 2022 21,655,000 -61,040,000 -50,334,000 130,096,453 103,384,928 -57,044,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-0.39

Peers — same industry

TickerNameMarket CapLastDaily %
ABEO ABEONA THERAPEUTICS INC. $312.90M $5.49
RZLT Rezolute, Inc. $317.76M $3.30
TENX TENAX THERAPEUTICS, INC. $317.77M $11.98
RCKT ROCKET PHARMACEUTICALS, INC. $327.58M $3.00
ELDN Eledon Pharmaceuticals, Inc. $300.26M $3.89

News headlines (Yahoo Finance, 1h cache)

European Equities Traded in the US as American Depositary Receipts Track Higher in Tuesday Trading
2026-05-26 15:09 · Yahoo
European Equities Traded in the US as American Depositary Receipts Edge Higher in Friday Trading
2026-05-22 15:06 · Yahoo
European Equities Traded in US as ADRs Rise in Wednesday Trading
2026-05-20 15:03 · Yahoo
European Equities Traded in the US as American Depositary Receipts Trend Lower in Tuesday Trading
2026-05-19 15:27 · Yahoo
European Equities Traded in the US as American Depositary Receipts Down Sharply in Friday Trading
2026-05-15 15:04 · Yahoo
European Equities Traded in the US as American Depositary Receipts Decline Sharply in Tuesday Trading
2026-05-12 15:14 · Yahoo
Silence Therapeutics to Participate in H.C. Wainwright BioConnect Investor Conference
2026-05-12 12:00 · Yahoo
This Silence Therapeutics Insider Increased Their Holding In The Last Year
2026-05-12 10:07 · Yahoo
European Equities Traded in the US as American Depositary Receipts Start Week on Flat Note in Monday Trading
2026-05-11 15:05 · Yahoo
European Equities Traded in the US as American Depositary Receipts Heading Lower in Thursday Trading
2026-05-07 15:10 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.