SPRO — Spero Therapeutics, Inc.

Nasdaq · Health Care · Pharmaceuticals · CIK 1701108 ·
Last close
$2.86
Market Cap
$165.60M
52W High
$2.94
52W Low
$2.11
ADV30
555,232
Next earnings
2026-08-11
Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 258,000 -7,538,000 -7,203,000 59,021,000 56,129,000 6,087,000
Dec 2025 39,658,000 31,405,000 31,520,000 68,919,000 40,265,000 9,898,000
Sep 2025 3,048,000 -7,329,000 -7,382,000 54,170,000 48,616,000 27,676,000
Jun 2025 11,802,000 -2,361,000 -1,700,000 62,119,000 31,194,000 29,291,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-12,624,000
Investing CF
Financing CF
$0
CapEx
Dividends Paid
Buybacks
EPS Diluted TTM
$0.12
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-451,066,000
Inventory
Receivables
$25,387,000
ST Investments
EBIT TTM
$7,159,000
Pretax Income TTM
$8,833,000
Interest Exp TTM
Analysts
1

Yahoo Snapshot (yfinance, live)

Total Revenue
$61,186,000
EBITDA
Free Cash Flow
$13,691,625
Enterprise Value
$106,153,120
Total Cash
$56,129,000
Total Debt
$2,474,000
Shares Out
57,901,493
Trailing EPS
$0.27
Book Value
$1.05
ROE
35.1%
ROA
13.0%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 59,619,000 7,159,000 8,572,000 68,919,000 9,898,000 -12,624,000
Dec 2024 27,396,000 -72,484,000 -68,566,000 110,543,000 64,420,000 -23,444,000
Dec 2023 96,735,000 26,787,000 22,806,000 182,390,000 75,496,000 -32,995,000
Dec 2022 48,579,000 -30,567,000 -46,415,000 124,802,000 48,868,000 -7,731,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-1.11

Peers — same industry

TickerNameMarket CapLastDaily %
PRQR ProQR Therapeutics N.V. $165.42M $1.57
ORMP ORAMED PHARMACEUTICALS INC. $165.34M $4.04
ENLV Enlivex Ltd. $164.88M $0.68
OKUR OnKure Therapeutics, Inc. $166.43M $4.12
HRTX HERON THERAPEUTICS, INC. /DE/ $167.19M $0.88

News headlines (Yahoo Finance, 1h cache)

Promising Penny Stocks To Consider In May 2026
2026-05-15 12:05 · Yahoo
Spero Therapeutics Announces First Quarter 2026 Operating Results and Provides Business Update
2026-05-13 20:05 · Yahoo
Inventiva Builds Up Leadership Team Ahead of Potential Commercialization
2026-04-22 22:03 · Yahoo
Uncovering 3 Penny Stocks With Market Caps Under $700M
2026-04-08 18:05 · Yahoo
Spero Therapeutics Announces Fourth Quarter and Full Year 2025 Operating Results and Provides a Business Update
2026-03-26 20:05 · Yahoo
Spero Therapeutics to Report Fourth Quarter and Full Year 2025 Financial Results and Provide Business Update on March 26, 2026
2026-03-18 20:05 · Yahoo
Airgain And 2 Other Promising Penny Stocks
2026-02-05 18:06 · Yahoo
3 Promising Penny Stocks With Market Caps Up To $300M
2026-01-07 18:05 · Yahoo
Spero Announces NDA Resubmission of Tebipenem HBr by GSK to the FDA for the Treatment of Complicated Urinary Tract Infections, Including Pyelonephritis
2025-12-19 13:00 · Yahoo
Is Spero Therapeutics (NASDAQ:SPRO) In A Good Position To Deliver On Growth Plans?
2025-12-15 10:20 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.