VCNX — VACCINEX, INC.

OTC · Health Care · Pharmaceuticals · CIK 1205922 ·
Last close
$1.29
Market Cap
$3.45M
52W High
$1.50
52W Low
$0.76
ADV30
2,591
Next earnings
Vaccinex, Inc., a clinical-stage biotechnology company, engages in the discovery and development of targeted biotherapeutics to treat cancer, neurodegenerative diseases, and autoimmune disorders. The company's lead drug candidate is pepinemab, a humanized monoclonal antibody that binds and blocks the activity of SEMA4D. It is developing Pepinemab, which is in phase 2 clinical for the treatment of Alzheimer's disease and has completed phase 2 study for the treatment of Huntington's disease; Pepinemab in combination with Pembrolizumab in phase 2 study for head and neck cancer; Pepinemab in combination with Avelumab in phase 2 study for pancreatic cancer, and completed phase 2 clinical trial with Avelumab for non-small cell lung cancer; and Pepinemab in combination with Nivolumab and/or Ipilimumab which is in phase 2 clinical trial for melanoma; Pepinemab in combination with Trastuzumab and dendritic cell vaccines in phase 2 clinical trial for breast cancer. The company has also developed ActivMAb, a human antibody discovery platform based on a novel method for expressing and presenting complex multipass membrane proteins, as well as full-length human monoclonal antibodies on the surface of mammalian pox viruses. In addition, it develops CHS-114 and anti-CCR8 antibody; and VX5, which is in preclinical development to treat related to autoimmune disorders.It has collaborations with Merck Sharp & Dohme; Ares Trading S.A.; Emory University; Huntington Study Group; Catalent Pharma Solutions, LLC; and Surface Oncology, Inc. The company was incorporated in 2001 and is headquartered in Rochester, New York.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Dec 2024 213,000 -3,387,000 -3,374,000 2,596,000 1,107,000 5,084,000
Sep 2024 52,000 -4,552,000 -5,732,000 4,854,000 2,906,000 6,175,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-7,139,000
Investing CF
$-8,000
Financing CF
$8,021,000
CapEx
$-8,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-2.83
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-358,561,000
Inventory
Receivables
$838,000
ST Investments
EBIT TTM
$-9,104,000
Pretax Income TTM
$-9,106,000
Interest Exp TTM
$2,000
Analysts

Yahoo Snapshot (yfinance, live)

Total Revenue
$601,000
EBITDA
$-18,641,000
Free Cash Flow
$-11,543,625
Enterprise Value
$4,035,861
Total Cash
$1,107,000
Total Debt
$25,000
Shares Out
2,676,637
Trailing EPS
$-9.79
Book Value
$-1.55
ROE
ROA
-376.1%
Div Yield

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2024 601,000 -18,735,000 -18,634,000 2,596,000 5,084,000 -16,186,000
Dec 2023 570,000 -22,885,000 -20,251,000 3,631,000 5,942,000 -21,379,000
Dec 2022 275,000 -19,906,000 -19,815,000 7,977,000 2,784,000 -19,074,000
Dec 2021 900,000 -22,490,000 -22,380,000 9,843,000 2,431,000 -25,298,000

TTM Snapshot

Revenues TTM
NetIncome TTM
OpCashFlow TTM
Assets (Latest)
Forward EPS
$-0.14

Peers — same industry

TickerNameMarket CapLastDaily %
ONCO Onconetix, Inc. $3.47M $0.94
SBFM Sunshine Biopharma Inc. $3.38M $2.09
UPC Universe Pharmaceuticals INC $3.33M $5.27
PMHS Polomar Health Services, Inc. $3.31M $0.12
PPCB Propanc Biopharma, Inc. $3.67M $1.61

News headlines (Yahoo Finance, 1h cache)

Vaccinex to Report New Biomarker Data and Plans for Phase 2B Clinical Trial of Pepinemab in AD at the Alzheimer’s Association International Conference in London on July 13, 2026
2026-07-08 12:30 · Yahoo
Vaccinex, Inc. Announces $60 million Agreement to Finance a Phase 2b clinical trial of pepinemab to treat Alzheimer’s Disease
2025-12-23 13:01 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.