SION — Sionna Therapeutics, Inc.

Nasdaq · Health Care · Pharmaceuticals · CIK 2036042 ·
Last close
$42.88
Market Cap
$1.94B
52W High
$48.44
52W Low
$32.56
ADV30
435,959
Next earnings
Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109, an intracellular loop 4 directed CFTR corrector that has completed Phase 1 trial; SION-2851, a TMD1-directed CFTR corrector that has completed Phase 1 trial; SION-451, which is nucleotide-binding domain 1 stabilizer in Phase 1 trial; and SION-719, which is nucleotide-binding domain 1 stabilizer in Phase 2a proof-of-concept trial. The company was formerly known as Sling Therapeutics, Inc. and changed its name to Sionna Therapeutics, Inc. in July 2021. Sionna Therapeutics, Inc. was incorporated in 2019 and is headquartered in Waltham, Massachusetts.

Quarterly Fundamentals

Revenues vs Net Income (last 4 Q)

Assets vs Liabilities (last 4 Q)

PeriodRevenuesGrossProfit OpIncomeNetIncomeAssets CashLiabilities
Mar 2026 0 -29,599,000 -26,779,000 305,039,000 63,324,000 16,831,000
Dec 2025 0 -23,612,000 -20,440,000 325,953,000 58,451,000 19,120,000
Sep 2025 0 -23,805,000 -20,278,000 339,270,000 50,831,000 17,602,000
Jun 2025 0 -21,906,000 -18,068,000 352,048,000 40,985,000 15,619,000

Cashflow TTM (yfinance, fills SEC gap)

Operating CF
$-66,297,000
Investing CF
$-118,749,000
Financing CF
$205,710,000
CapEx
$-377,000
Dividends Paid
Buybacks
EPS Diluted TTM
$-1.95
As of
2026-05-10

Balance + Analyst (yfinance extras)

Retained Earnings
$-256,354,000
Inventory
Receivables
ST Investments
$177,431,000
EBIT TTM
$-88,982,000
Pretax Income TTM
$-75,268,000
Interest Exp TTM
Analysts
10

Annual Trend (SEC EDGAR, last 4y)

Revenues vs Net Income (last 4y)

FY endRevenuesOpIncome NetIncomeAssetsLiabilities EquityOCF
Dec 2025 0 -88,982,000 -75,268,000 325,953,000 19,120,000 -66,297,000
Dec 2024 0 -70,556,000 -61,688,000 185,752,000 349,465,000 -52,787,000
Dec 2023 0 -50,333,000 -47,263,000 51,945,000 166,826,000 -43,699,000
Dec 2022 0 -41,372,000 -40,240,000 87,369,000 157,293,000 -36,068,000

TTM Snapshot

Revenues TTM
$2,566,000
NetIncome TTM
$-8,552,000
OpCashFlow TTM
$0
Assets (Latest)
$185,752,000
Forward EPS
$-2.80

Peers — same industry

TickerNameMarket CapLastDaily %
STOK Stoke Therapeutics, Inc. $1.93B $31.03
AUPH Aurinia Pharmaceuticals Inc. $1.95B $15.19
RAPP Rapport Therapeutics, Inc. $1.90B $39.71
NBTX Nanobiotix S.A. $1.98B $40.80
AAPG ASCENTAGE PHARMA GROUP INTERNATIONAL $1.88B $20.13

News headlines (Yahoo Finance, 1h cache)

Wedbush Initiates Coverage of Sionna Therapeutics (SION)
2026-05-14 16:52 · Yahoo
Sionna Therapeutics to Participate in the 2026 RBC Capital Markets Global Healthcare Conference
2026-05-13 12:00 · Yahoo
Sionna Therapeutics Reports First Quarter 2026 Financial Results
2026-05-12 11:00 · Yahoo
A Look At Sionna Therapeutics (SION) Valuation After Its Strong 1 Year Return And Premium P/B Ratio
2026-05-05 14:11 · Yahoo
Sionna Insider Sells $2.5 Million in Stock Amid 215% Surge, but Here's What Investors Should Watch
2026-04-27 19:49 · Yahoo
Sionna Therapeutics Completes Enrollment in PreciSION CF Phase 2a Trial Evaluating NBD1 Stabilizer, SION-719, Added to Standard of Care in Participants with Cystic Fibrosis
2026-04-27 11:00 · Yahoo
Sionna Therapeutics to Participate in the Raymond James 2026 Biotech Innovation Symposium
2026-04-07 11:00 · Yahoo
Sionna Chief Legal Officer Cashed Out Her Shares. Her Options Are Another Story
2026-03-31 01:28 · Yahoo
Sionna Stock Is Up 144% This Past Year. Is the Biotech a Buy as One Fund Makes a $7 Million Bet?
2026-03-18 15:49 · Yahoo
This Investor Sold $5 Million of a Biotech Stock Up 118% in a Year, but Here's Why It Still Seems Bullish on Shares
2026-03-15 22:27 · Yahoo

Recent Insider Activity

No insider activity indexed for this ticker.